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Cathepsin L as a protease responsible for proteolytically processing the N-terminal H3 tail. Cell. 2008 Oct 17;135(2):284-94.
Chromatin is the complex basis of DNA and protein that makes up chromosomes. Changes in chromatin structure are affected by chemical modifications of histone proteins such as methylation (DNA and proteins) and acetylation (proteins), and by non-histone, DNA-binding proteins.